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1

Pharmacokinetics of ciprofloxacin XR (1000 mg) versus levofloxacin (500 mg) in plasma and urine of male and female healthy volunteers receiving a single oral dose

Florian M.E. Wagenlehner, Martina Kinzig-Schippers, Uwe Tischmeyer, Christine Wagenlehner, Fritz Sörgel, Axel Dalhoff, Kurt G. Naber

Journal:

International Journal of Antimicrobial Agents

Year:

2006

Language:

english

File:

PDF, 179 KB

english, 2006

2

The contamination of valsartan and other sartans, Part 2: Untargeted Screening reveals contamination with amides additionally to known nitrosamine impurities

Scherf-Clavel, Oliver, Kinzig, Martina, Besa, Axel, Schreiber, André, Bidmon, Clemens, Abdel-Tawab, Mona, Wohlfart, Jonas, Sörgel, Fritz, Holzgrabe, Ulrike

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2019

Language:

english

File:

PDF, 528 KB

english, 2019

3

Nonlinear pharmacokinetics of piperacillin in healthy volunteers – implications for optimal dosage regimens

Jürgen B. Bulitta, Martina Kinzig, Verena Jakob, Ulrike Holzgrabe, Fritz Sörgel, Nicholas H. G. Holford

Journal:

British Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.88 MB

english, 2010

4

Comparability of Biosimilar Filgrastim with Originator Filgrastim: Protein Characterization, Pharmacodynamics, and Pharmacokinetics

Sörgel, Fritz, Schwebig, Arnd, Holzmann, Johann, Prasch, Stefan, Singh, Pritibha, Kinzig, Martina

Journal:

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

5

Assessment of Pharmacokinetic Drug–Drug Interactions in Humans: In Vivo Probe Substrates for Drug Metabolism and Drug Transport Revisited

Fuhr, Uwe, Hsin, Chih-hsuan, Li, Xia, Jabrane, Wafaâ, Sörgel, Fritz

Journal:

Annual Review of Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.21 MB

english, 2019

6

The contamination of valsartan and other sartans, part 1: New findings

Sörgel, Fritz, Kinzig, Martina, Abdel-Tawab, Mona, Bidmon, Clemens, Schreiber, André, Ermel, Steffen, Wohlfart, Jonas, Besa, Axel, Scherf-Clavel, Oliver, Holzgrabe, Ulrike

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2019

Language:

english

File:

PDF, 626 KB

english, 2019

7

Phenotyping ofN-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure

Alexander Jetter, Martina Kinzig-Schippers, Michael Illauer, Robert Hermann, Katharina Erb, Jürgen Borlak, Helga Wolf, Gillian Smith, Ingolf Cascorbi, Fritz Sörgel, Uwe Fuhr

Journal:

European Journal of Clinical Pharmacology

Year:

2004

Language:

english

File:

PDF, 342 KB

english, 2004

8

Mesalazine pharmacokinetics and NAT2 phenotype

Hendrik Lück, Martina Kinzig, Alexander Jetter, Uwe Fuhr, Fritz Sörgel

Journal:

European Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 179 KB

english, 2009

9

Comparison of the probability of target attainment between ceftriaxone and cefepime in the cerebrospinal fluid and serum against Streptococcus pneumoniae

Thomas P. Lodise Jr., Roland Nau, Martina Kinzig, Ronald N. Jones, G.L. Drusano, Fritz Sörgel

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2007

Language:

english

File:

PDF, 491 KB

english, 2007

10

Penetration of Antibacterials into Bone

Cornelia B. Landersdorfer, Jürgen B. Bulitta, Martina Kinzig, Ulrike Holzgrabe, Prof. Dr Fritz Sörgel

Journal:

Clinical Pharmacokinetics

Year:

2009

Language:

english

File:

PDF, 387 KB

english, 2009

11

Supplement 5. Second International Symposium on New Quinolones || Metabolism and Distribution of New Gyrase Inhibitors in the Isolated Perfused Rat Liver

Christoph Labisch, Rainer Metz, Hartmut Vergin, Waldemar Fabian, Gerhard Mahr, Peter Muth and Fritz Sörgel

Journal:

Reviews of Infectious Diseases

Year:

1989

Language:

english

File:

PDF, 271 KB

english, 1989

12

Penetration of Ciprofloxacin into Prostatic Fluid, Ejaculate and Seminal Fluid in Volunteers after an Oral Dose of 750 MG

Naber, Kurt G., Sörgel, Fritz, Kinzig, Martina, Weigel, Daniela M.

Journal:

The Journal of Urology

Year:

1993

File:

PDF, 111 KB

1993

13

The True Composition of Kidney Stones Passed During Triamterene Therapy

Sörgel, Fritz, Ettinger, Bruce, Benet, Leslie Z.

Journal:

The Journal of Urology

Year:

1985

Language:

english

File:

PDF, 122 KB

english, 1985

14

A long‐time stability study of 50 drug substances representing common drug classes of pharmaceutical use

Zilker, Markus, Sörgel, Fritz, Holzgrabe, Ulrike

Journal:

Drug Testing and Analysis

Year:

2019

Language:

english

File:

PDF, 470 KB

english, 2019

15

A HILIC-MS/MS assay for the quantification of metformin and sitagliptin in human plasma and urine: A tool for studying drug transporter perturbation

Scherf-Clavel, Oliver, Kinzig, Martina, Stoffel, Marc S., Fuhr, Uwe, Sörgel, Fritz

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2019

Language:

english

File:

PDF, 1010 KB

english, 2019

16

Pharmakokinetik der Chinolone: Wie gut wirken die Gyrasehemmeř

Fritz Sörgel, J. Bulitta, M. Kinzig-Schippers

Journal:

Pharmazie in unserer Zeit

Year:

2001

Language:

german

File:

PDF, 554 KB

german, 2001

17

Liquid chromatographic analysis of triamterene and its major metabolite, hydroxytriamterene sulfate, in blood, plasma, and urine

Fritz SÖRgel, Emil T. Lin, Jiro Hasegawa, Leslie Z. Benet

Journal:

Journal of Pharmaceutical Sciences

Year:

1984

Language:

english

File:

PDF, 309 KB

english, 1984

18

Metabolic fate and solubility of triamterene—not an explanation for triamterene nephrolithiasis

Fritz Sörgel, Bruce Ettinger, Leslie Z. Benet

Journal:

Journal of Pharmaceutical Sciences

Year:

1986

Language:

english

File:

PDF, 430 KB

english, 1986

19

Gas-liquid chromatography-mass spectroscopy determination of clopamide in plasma

Wolfgang Stüber, Henning Blume, Fritz Sörgel, Gerd Stenzhorn

Journal:

Journal of Pharmaceutical Sciences

Year:

1989

Language:

english

File:

PDF, 351 KB

english, 1989

20

Effect of probenecid on the distribution and elimination of ciprofloxacin in humans

Jaehde, Ulrich, Sörgel, Fritz, Reiter, Andreas, Sigl, Gabriele, Naber, Kurt G., Schunack, Walter

Journal:

Clinical Pharmacology & Therapeutics

Year:

1995

Language:

english

File:

PDF, 899 KB

english, 1995

21

An LC–MS/MS procedure for the quantification of naproxen in human plasma: Development, validation, comparison with other methods, and application to a pharmacokinetic study

Paul W. Elsinghorst, Martina Kinzig, Michael Rodamer, Ulrike Holzgrabe, Fritz Sörgel

Journal:

Journal of Chromatography B

Year:

2011

Language:

english

File:

PDF, 588 KB

english, 2011

22

Antibiotic therapy – rationale and evidence for optimal drug concentrations in prostatic and seminal fluid and in prostatic tissue

Kurt G. Naber, Fritz Sörgel

Journal:

Year:

2003

Language:

english

File:

PDF, 58 KB

english, 2003

23

Tissue pharmacokinetics of individual macrolides support observed differences in development of bacterial resistance

Shaip Krasniqi, Peter Matzneller, Martina Kinzig, Sven Hüttner, Fritz Sörgel, Markus Müller, Markus Zeitlinger

Journal:

BMC Pharmacology

Year:

2010

Language:

english

File:

PDF, 93 KB

english, 2010

24

Bioequivalence of HX575 (recombinant human epoetin alfa) and a comparator epoetin alfa after multiple intravenous administrations: an open-label randomised controlled trial

Fritz Sörgel, Ursula Thyroff-Friesinger, Andrea Vetter, Bernhard Vens-Cappell, Martina Kinzig

Journal:

BMC Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 924 KB

english, 2009

25

Zur Pharmakokinetik von Linezolid und Telithromycin: Zwei neue Antibiotika mit besonderen Eigenschaften

Fritz Sörgel, Cornelia Landersdorfer, Jürgen Bulitta

Journal:

Pharmazie in unserer Zeit

Year:

2004

Language:

german

File:

PDF, 732 KB

german, 2004

26

Editorial: Pharmazie in unserer Zeit 1/2004

Ulrike Holzgrabe, Fritz Sörgel

Journal:

Pharmazie in unserer Zeit

Year:

2004

Language:

german

File:

PDF, 112 KB

german, 2004

27

Pharmakokinetik und Pharmakodynamik der β-Lactame: Was wir über β-Lactame wissen und was wir wissen möchten

Fritz Sörgel, Jürgen Bulitta, Cornelia Landersdorfer

Journal:

Pharmazie in unserer Zeit

Year:

2006

Language:

german

File:

PDF, 527 KB

german, 2006

28

Editorial: Pharmazie in unserer Zeit 5/2006

Fritz Sörgel, Ulrike Holzgrabe

Journal:

Pharmazie in unserer Zeit

Year:

2006

Language:

german

File:

PDF, 96 KB

german, 2006

29

Phenotyping ofN-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected?

Alexander Jetter, Martina Kinzig, Michael Rodamer, Dorota Tomalik-Scharte, Fritz Sörgel, Uwe Fuhr

Journal:

European Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 172 KB

english, 2009

30

Development and validation of a liquid chromatography/tandem mass spectrometry procedure for the quantification of sunitinib (SU11248) and its active metabolite, N-desethyl sunitinib (SU12662), in human plasma: Application to an explorative study

Michael Rodamer, Paul W. Elsinghorst, Martina Kinzig, Michael Gütschow, Fritz Sörgel

Journal:

Journal of Chromatography B

Year:

2011

Language:

english

File:

PDF, 327 KB

english, 2011

31

Inhibition of flucloxacillin tubular renal secretion by piperacillin

Cornelia B. Landersdorfer, Carl M. J. Kirkpatrick, Martina Kinzig, Jürgen B. Bulitta, Ulrike Holzgrabe, Fritz Sörgel

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 1001 KB

english, 2008

32

Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid

Cornelia B. Landersdorfer, Carl M. J. Kirkpatrick, Martina Kinzig, Jürgen B. Bulitta, Ulrike Holzgrabe, Ulrich Jaehde, Andreas Reiter, Kurt G. Naber, Michael Rodamer, Fritz Sörgel

Journal:

British Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 868 KB

english, 2010

33

Antibiotic therapy — rationale and evidence for optimal drug concentrations in prostatic and seminal fluid and in prostatic tissue

Dr. Kurt G. Naber, Fritz Sörgel

Journal:

Year:

2003

Language:

english

File:

PDF, 469 KB

english, 2003

34

Pharmacokinetics and pharmacodynamics of fluoroquinolones

George Drusano, Marie-Thérèse Labro, Otto Cars, Paul Mendes, Pramod Shah, Fritz Sörgel, Willi Weber

Journal:

Clinical Microbiology and Infection

Year:

1998

Language:

english

File:

PDF, 1.07 MB

english, 1998

35

Plasma protein binding of gyrase inhibitors

Gabriele Zlotos, Annegret Buücker, Martina Kinzig-Schippers, Fritz Sorgel, Ulrike Holzgrabe

Journal:

Journal of Pharmaceutical Sciences

Year:

1998

Language:

english

File:

PDF, 77 KB

english, 1998

36

Oral triamterene disposition

Sörgel, Fritz, Hasegawa, Jiro, Lin, Emil T, Williams, Roger L

Journal:

Clinical Pharmacology & Therapeutics

Year:

1985

Language:

english

File:

PDF, 469 KB

english, 1985

37

Altered disposition of fleroxacin in patients with cystic fibrosis

Mimeault, Joëlle, Vallée, François, Seelmann, Robert, Sörgel, Fritz, Ruel, Michel, LeBel, Marc

Journal:

Clinical Pharmacology & Therapeutics

Year:

1990

Language:

english

File:

PDF, 866 KB

english, 1990

38

Intravenous ciprofloxacin disposition in obesity

Allard, Sylvie, Kinzig, Martina, Boivin, Guy, Sörgel, Fritz, Lebel, Marc

Journal:

Clinical Pharmacology & Therapeutics

Year:

1993

Language:

english

File:

PDF, 918 KB

english, 1993

39

Comparison of Tissue Concentrations After Intramuscular and Topical Administration of Ketoprofen

Irmgard Tegeder, Jörn Lötsch, Martina Kinzig-Schippers, Fritz Sörgel, Gary R. Kelm, Stephen T. Meller, Gerd Geisslinger

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 218 KB

english, 2001

40

Pharmacokinetics of triamterene and its metabolite in man

Jiro Hasegawa, Emil T. Lin, Roger L. Williams, Fritz Sörgel, Leslie Z. Benet

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1982

Language:

english

File:

PDF, 771 KB

english, 1982

41

Brief report: Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration

Kurt G. Naber, Fritz Sörgel, Frieder Kees, Ulrich Jaehde, Harald Schumacher

Journal:

The American Journal of Medicine

Year:

1989

Language:

english

File:

PDF, 378 KB

english, 1989

42

Brief report: Gastrointestinal secretion of ciprofloxacin: Evaluation of the charcoal model for investigations in healthy volunteers

Fritz Sörgel, Kurt G. Naber, Ulrich Jaehde, Andreas Reiter, Robert Seelmann, Gabriele Sigl

Journal:

The American Journal of Medicine

Year:

1989

Language:

english

File:

PDF, 448 KB

english, 1989

43

Comparative pharmacokinetics of ciprofloxacin and temafloxacin in humans: A review

Fritz Sörgel, Kurt G. Naber, Martina Kinzig, Gerhard Mahr, Peter Muth

Journal:

The American Journal of Medicine

Year:

1991

Language:

english

File:

PDF, 1.95 MB

english, 1991

44

Comparison of the pharmacokinetics and pharmacodynamic profile of carumonam in cystic fibrosis patients and healthy volunteers

Jürgen B. Bulitta, Stephen B. Duffull, Cornelia B. Landersdorfer, Martina Kinzig, Ulrike Holzgrabe, Ulrich Stephan, George L. Drusano, Fritz Sörgel

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2009

Language:

english

File:

PDF, 907 KB

english, 2009

45

Comparison of 30-min and 3-h infusion regimens for imipenem/cilastatin and for meropenem evaluated by Monte Carlo simulation

Lois S. Lee, Martina Kinzig-Schippers, Anne N. Nafziger, Lei Ma, Fritz Sörgel, Ronald N. Jones, George L. Drusano, Joseph S. Bertino Jr.

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2010

Language:

english

File:

PDF, 317 KB

english, 2010

46

Bioequivalence Studies of Omnitrope, the First Biosimilar/rhGH Follow-on Protein: Two Comparative Phase 1 Randomized Studies and Population Pharmacokinetic Analysis

Stanhope, Richard, Sörgel, Fritz, Gravel, Patricia, Schuetz, Yannic B. Pannatier, Zabransky, Markus, Muenzberg, Michael

Journal:

Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 451 KB

english, 2010

47

Lipophilicity at pH 7.4 and molecular size govern the entry of the free serum fraction of drugs into the cerebrospinal fluid in humans with uninflamed meninges

Roland Nau, Fritz Sörgel, Hilmar W. Prange

Journal:

Journal of the Neurological Sciences

Year:

1994

Language:

english

File:

PDF, 472 KB

english, 1994

48

Urinary bactericidal activity, urinary excretion and plasma concentrations of gatifloxacin (400 mg) versus ciprofloxacin (500 mg) in healthy volunteers after a single oral dose

Dieter Boy, Michaela Well, Martina Kinzig-Schippers, Fritz Sörgel, Dorothe Ankel-Fuchs, Kurt G Naber

Journal:

International Journal of Antimicrobial Agents

Year:

2004

Language:

english

File:

PDF, 342 KB

english, 2004

49

Concentrations in plasma, urinary excretion and bactericidal activity of levofloxacin (500 mg) versus ciprofloxacin (500 mg) in healthy volunteers receiving a single oral dose

Florian M.E. Wagenlehner, Martina Kinzig-Schippers, Fritz Sörgel, W. Weidner, Kurt G. Naber

Journal:

International Journal of Antimicrobial Agents

Year:

2006

Language:

english

File:

PDF, 535 KB

english, 2006

50

Urinary bactericidal activity and pharmacokinetics of enoxacin versus norfloxacin and ciprofloxacin in healthy volunteers after a single oral dose

Michaela Well, Kurt G. Naber, M. Kinzig-Schippers, Fritz Sörgel

Journal:

International Journal of Antimicrobial Agents

Year:

1998

Language:

english

File:

PDF, 89 KB

english, 1998